High-energy blue light is a growing concern because of the higher exposure from multiple sources including sunlight, energy-efficient lighting and digital devices, the latter of which has increased substantially with the rise in screen time across all age groups. The need to help protect the eye from its damaging effects are immediate. Of the more than 600 carotenoids found in nature, only three- lutein,RR-zeaxanthin and RS-zeaxanthin-also known as meso-zeaxanthin- are found in the eye. The three carotenoids- lutein,RR-and RS-zeaxanthin- make up macular pigment, which is located at the very back of the eye in the macula, the area of the retina responsible for highest visual performance. However, this area of the eye is also susceptible to the greatest amount of photo-oxidative damage. Together, lutein and the zeaxanthin isomers absorb a broad spectrum of high-energy blue light, which offers greater protection of retinal tissue.