April 6, 2016



Presented at Experimental Biology, the new study provided evidence supporting the weight management benefits of capsaicinoids.

The burning sensation one gets when eating chili peppers comes from capsaicinoids in the plant, the highlight compound of OmniActive’s Capsimax ingredient, marketed for weight management applications.

The research, titled Capsaicinoids Supplementation Reduces Appetite and Body Circumferences in Healthy Men and Women: A Placebo Controlled Randomized Double Blind Study, was presented by the company’s Senior Manager of Global Scientific and Clinical Affairs Vijaya Juturu at the ongoing Experimental Biology conference in San Diego, CA. The abstract is available through The Official Journal of the Federation of American Societies for Experimental Biology.

 "The data showed that Capsimax Capsicum Extract may be beneficial for decreasing measures of appetite, which can support weight management," Lynda Doyle, VP of Global Market, OmniActive Health Technologies, said in a press release. "We are excited to further expand our growing research surrounding Capsimax."

The study was conducted by scientists from the University of Mary HardinBaylor (Belton, TX), Auburn University (Auburn, AL), and Increnovo LLC (Milwaukee, WI), and supported financially by OmniActive Health Technologies.

Study method

The double blind, randomized, placebo controlled study was done on 77 healthy males and females, randomly assigned by fat mass to ingest either 2mg or 4mg of Capsimax, or a placebo.

The Abstract also explained the participants were requested to keep their usual diet and physical activity, with some restriction of spicy food and instructions on caloric intake. The pills were taken with 8 oz of water after breakfast.


According to the report, the waist to hip ratio measurements showed a main effect for time with post-hoc tests revealing a significant decrease in the 2mg Capsimax group from the first day of study to the sixth week. Moreover, there were no significant changes observed in clinical blood safety markers at both doses of Capsimax.

“These findings show evidence to support that the dietary supplementation of CAP has beneficial effects on anthropometric parameters (waist and hip circumferences) and appetite suppression,” the study said.

“Further long-term studies in relation to other metabolic factors are warranted,” they added.

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