Vijaya Juturu Ph.D., F.A.C.N., Manager of Global Scientific and Clinical Affairs with OmniActive Health Technologies presented two posters on emerging science surrounding highly soluble curcumin (CurcuWIN) during this year’s Experimental Biology (EB) meeting which ran from March 28th to April 1st at the Boston Convention and Exhibit Center, Boston, Massachusetts (US). The curcumin posters were based on in vitro and in vivo model studies conducted by OmniActive in collaboration with researchers from Firat University (Turkey).
The first study—Curcumin (CurcuWIN) Improves Antioxidant Capacity and Reduces Inflammation Following Downhill Running-Induced Muscle Damage—investigated the effects of curcumin supplementation on changes in serum parameters and antioxidant status of muscle in rats after exhaustive exercise on a motor-driven rodent treadmill. A significant decrease in LDL-cholesterol and triglycerides was also observed in CurcuWIN treated groups. These results suggest CurcuWIN is a potential ingredient for preventing muscle damage as well as improving exercise performance and increase in time of exhaustion.
In the other study—Antioxidant Properties and Safety Evaluation of Curcumin (CurcuWIN)—the antioxidant effects and safety of curcumin supplementation in rats was monitored for a period of 6 weeks. CurcuWIN’s antioxidant effects were shown by significant decrease in muscle oxidative stress markers and the significant improvements in antioxidant enzymes in curcumin treated groups. Demonstrating the safety of CurcuWIN, no treatment related changes in liver and kidney functions, and no histopathological changes were observed. Study results indicate that CurcuWIN is safe, has antioxidant properties and reduces oxidative stress markers.
“There is an immense breadth of science suggesting that curcumin has tremendous health benefits, and these two particular studies show the advantages of CurcuWIN—a safe form of highly soluble curcumin, with new and unique science showing its enhanced anti-inflammatory and antioxidant properties,” stated Dr. Juturu. “The results of both of these studies have huge implications on the future success of this potent ingredient.”
CurcuWIN is a highly bioavailable form of curcumin. In a well-controlled human clinical trial—the first curcumin study of its kind—comparing commercial curcumin products, CurcuWIN increased relative absorption of total curcuminoids 46 times over standard curcumin. In the same trial, CurcuWIN was shown to be significantly more bioavailable than other enhanced commercial forms of curcumin. Nutrition Journal published the study results on January 24, 2014.
“OmniActive is engaged in studies like these as we continue to contribute to the growing science of innovative forms of curcuminoids, such as CurcuWIN,” noted Jayant Deshpande, Ph.D., CTO, OmniActive. “These studies further broaden the usage of curcuminoids into a variety of novel formulations”.
In October 2014, OmniActive won an award at the American College of Nutrition’s (ACN) 55th Annual Conference in San Antonio, TX (USA) for the poster Soluble Curcumin (CurcuWIN) in the Prevention of Diabetic Retinopathy via Modulation of Antioxidant Activity and Genetic Pathways in Vivo Model.
About EB meeting: A multi-society, interdisciplinary meeting, Experimental Biology features plenary and award lectures, as well as a variety of speaker and poster sessions, symposia, and career services. EB also exhibits scientific equipment, supplies, and publications. With attendance by 14,000 of the top researchers, scientists and exhibitors, EB showcases the latest science surrounding anatomy, physiology, pathology, biochemistry, nutrition and pharmacology. EB is sponsored by The American Society for Nutrition (ASN); The American Association of Anatomists (AAA); The American Physiological Society (APS); American Society for Biochemistry and Molecular Biology (ASBMB); American Society for Investigative Pathology (ASIP); and American Society for Pharmacology and Experimental Therapeutics (ASPET).
About OmniActive Health Technologies, Inc.:
OmniActive Health Technologies (www.omniactives.com) offers a range of quality ingredients, which are innovative and scientifically validated for dietary supplementation, nutritional fortification, functional food/beverage, coloring,flavor enhancement and personal care applications. The company addresses complex challenges for customers in the dietary supplement, food and beverage space using technology-driven, sustainable solution with application support within a global regulatory framework. Whether looking for a new ingredient to add to a finished product, or an ingredient solution to enhance an existing ingredient, you will find unmatched innovation at OmniActives
Core products include carotenoids, plant extracts and specialty functional ingredients. OmniActives leverages international R&D strengths to deploy an array of state of the art manufacturing technologies in extraction,purification, isolation and delivery of nutritional actives. The company’s manufacturing operations are located at multiple sites in India and are cGMP and HACCP system compliant.