New Science Shows Lutemax 2020 Supports BDNF and Cognitive Performance

Morristown, N.J., September 20, 2019 – Lutemax® 2020 has been shown to positively affect cognitive performance, says a new publication entitled Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance, which was published in the journal Physiology and Behavior. The six-month randomized, double-blind, placebo-controlled study involved 59 young, healthy male and female subjects between 18-25 years of age.

Supplementation with Lutemax® 2020 showed significant relationships between the changes in serum/retinal levels of lutein and zeaxanthin isomers, brain-derived neurotrophic factor (BDNF) and reduced inflammation, which led to improvements in cognitive performance.

“Compelling results such as these lend credence to the idea that macular carotenoids play a vital role in not only the  eyes but also the brain by interrupting inflammatory pathways that can lead to a reduction in BDNF, which plays a role in learning and memory,” said James Stringham, Ph.D., co-researcher and author of the publication.

There is an accumulating body of science linking oxidative and inflammatory stress with reductions in neurotrophic factors such as BDNF, stress resilience, and cognitive function. Given the established antioxidant and anti-inflammatory capacity of the macular carotenoids in the eye, and that the eyes are an extension of neural tissue, the authors examined how supplementation with Lutemax® 2020 can impact BDNF and cognitive performance.

“This new publication on Lutemax® 2020 further strengthens the notion that the eyes and brain are connected, and supplementing with a combination of lutein, RS-zeaxanthin and RR (meso)-zeaxanthin can positively influence outcomes associated with vision, cognition and stress,” said Arun Balakrishnan, CSO, OmniActive Health Technologies. “As consumer demand for natural solutions to support cognitive function and performance continues to grow, our science shows that Lutemax® 2020 can fill this need in the market.”

For media opportunities, please contact Becky Wright at  and for more information on the study, Lutemax® 2020 or OmniActive’s many health focused solutions and services, please contact Sara Zoet at

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About Lutemax® 2020

Award-winning, globally-recognized Lutemax 2020 is a naturally-derived marigold extract providing all three macular carotenoids—lutein and enhanced levels of both zeaxanthin isomers (RR-and RS [meso]-zeaxanthin)—at the same 5:1 ratio as found naturally in the diet. This unique combination of lutein with zeaxanthin isomers makes Lutemax 2020 a convenient, cost effective way to boost the benefits of your eye health formulation.


About OmniActive Health Technologies

OmniActive Health Technologies is a health-solutions provider, offering a wide range of scientifically-validated, branded ingredients to address complex challenges for customers in the dietary supplement, functional food and beverage spaces. Bringing added value to the global natural products industry for 15 years, OmniActive focuses on healthy living as well as healthy aging through IP-protected, science-backed nutritional innovations and solutions as well as specialty botanicals and extracts from natural sources.